2/11/2024 0 Comments Heparin antidote vitamin kread more, or antithrombin Antithrombin Deficiency Because antithrombin inhibits thrombin and factors Xa, IXa, and XIa, deficiency of antithrombin predisposes to venous thrombosis. read more, protein S Protein S Deficiency Because protein S binds and assists activated protein C in the degradation of coagulation factors Va and VIIIa, deficiency of protein S predisposes to venous thrombosis. ![]() (See also Overview of Thrombotic Disorders.) Protein C is a vitamin. read more or protein C Protein C Deficiency Because activated protein C degrades coagulation factors Va and VIIIa, deficiency of protein C predisposes to venous thrombosis. Patients with selected hypercoagulable states (eg, antiphospholipid syndrome Antiphospholipid Syndrome (APS) Antiphospholipid syndrome is an autoimmune disorder characterized by venous and arterial thrombosis or pregnancy complications (eg, recurrent miscarriage) and persistent autoantibodies to phospholipid-bound. Treatment is usually longer in patients receiving ongoing cancer therapy and in patients with advanced, metastatic disease. Patients with cancer-associated thrombosis should receive at least 3 months of anticoagulation. ![]() Patients with idiopathic (or unprovoked) DVT with no known risk factors, or recurrent DVT should take anticoagulants for at least 6 months and, in selected patients, probably for life unless they are at high risk for bleeding complications. Patients with transient risk factors for DVT (eg, immobilization, surgery) can usually stop taking anticoagulants after 3 to 6 months.
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